%0 Journal Article
%T 上海市闵行区某民办中学聚集性肺结核疫情分析
%A 唐利红
%A 沈鑫△
%A 苏华林
%A 王伟炳
%A 吴蕴华
%A 严慧琴
%A 孙华
%A 李静
%J 复旦大学（医学报）
%D 2017
%X </br>Objective To analyze the epidemiological characteristics of aggregation outbreaks of pulmonary tuberculosis (TB) in a private middle school in Minhang District ofShanghai.Methods Symptom and radiographic screening were performed on the students of Grade 3 in this senior high school. Epidemiological survey,sputum smear,culture and molecular epidemiological examination were conducted on suspected patients.Whole genome sequencing was completed on positive strains.Results In the screening of 49 close contacts with one TB patient (index case) in the school,a total of 10 patients with pulmonary TB were diagnosed,of which 3 cases were positive for culture.Another case was diagnosed and positive for culture after expanding the scope of screening. The genotype of the isolated strains from index case and the 4 patients positive for culture was identical to that of the first case of the classoneyear before,suggesting the transmission within the grade of Senior Three.Conclusions This is an aggregation outbreak that may be attributable to the first patient with positive bacteria.Therefore,timely diagnosis and effective treatment of pulmonary TB patients,as well as timely
%K &lt
%K /br&gt
%K pulmonary tuberculosis aggregate epidemic outbreak control
%U http://jms.fudan.edu.cn/CN/abstract/abstract1454.shtml