%0 Journal Article
%T Effects of Elasticity on Wall Shear Stress in Patient-Specific Aneurysm of Cerebral Artery
%A Ryuhei Yamaguchi
%A Taihei Kotani
%A Gaku Tanaka
%A Simon Tupin
%A Kahar Osman
%A Nadia Shaira Shafii
%A Ahmad Zahran Md Khudzari
%A Kazuhiro Watanabe
%A Hitomi Anzai
%A Atsushi Saito
%A Makoto Ohta
%J Journal of Flow Control, Measurement & Visualization
%P 73-86
%@ 2329-3330
%D 2019
%I Scientific Research Publishing
%R 10.4236/jfcmv.2019.72006
%X The behavior of wall shear stress (WSS) was previously reported in a deformable aneurysm model using fluid-structure interactions. However, these findings have not been validated. In the present study, we examined the effect of elasticity (<em>i.e.</em>, deformation) on wall shear stress inside a cerebral aneurysm at the apex of a bifurcation using particle image velocimetry<em> in vitro</em>. The flow model simulated a human patient-specific aneurysm at the apex of the bifurcation of the middle cerebral artery. Flow characteristics by wall elasticity were examined for both elastic and non-deformable aneurysm models with pulsatile blood flow. The absolute temporally- and spatially-averaged WSS along the bleb wall was smaller in the elastic model than that in the non-deformable model. This small WSS may be related to attenuation of the WSS. Further, the WSS gradient had a finite value near the stagnation point of the aneurysm dome. Finally, the WSS gradient near the stagnation point was slightly smaller in the elastic model than that in the non-deformable model. These data suggest that elasticity of the aneurysm wall can affect the progression and rupture of aneurysms via hemodynamic stress.
%K Cerebral Aneurysm
%K Elasticity
%K Particle Image Velocimetry
%K Wall Shear Stress
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=90571