%0 Journal Article
%T Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis
%A Gao-De Li
%J Open Access Library Journal
%V 6
%N 2
%P 1-5
%@ 2333-9721
%D 2019
%I Open Access Library
%R 10.4236/oalib.1105185
%X
More than 30 years ago, we published a paper entitled as ˇ°Abnormal Chromatin Configuration and Oncogenesisˇ±, which proposed the first hy-pothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis are presented.
%K Chromatin Configuration
%K Oncogenesis
%K 3D Genome
%K Cancer
%K Cell Differentiation
%K Cell Cycle
%K Gene Regulation
%K Gene Activity
%U http://www.oalib.com/paper/5303356