%0 Journal Article %T Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis %A Gao-De Li %J Open Access Library Journal %V 6 %N 2 %P 1-5 %@ 2333-9721 %D 2019 %I Open Access Library %R 10.4236/oalib.1105185 %X
More than 30 years ago, we published a paper entitled as ˇ°Abnormal Chromatin Configuration and Oncogenesisˇ±, which proposed the first hy-pothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis are presented.
%K Chromatin Configuration %K Oncogenesis %K 3D Genome %K Cancer %K Cell Differentiation %K Cell Cycle %K Gene Regulation %K Gene Activity %U http://www.oalib.com/paper/5303356