%0 Journal Article %T Highly-Controllable Imprinted Polymer Nanoshell on the Surface of Silica Nanoparticles for Selective Adsorption of 17<i>¦Ā</i>-Estradiol %A Xue Fu %A Bo Song %A Xiaozhen Chen %A An Wang %A Chun Wang %J Journal of Encapsulation and Adsorption Sciences %P 210-224 %@ 2161-4873 %D 2018 %I Scientific Research Publishing %R 10.4236/jeas.2018.84011 %X A highly-controllable core-shell silica-MIPs absorbent by anchoring a MIPs layer to the surface of SiO₂ nanoparticles via a surface molecular imprinting process was prepared. The templates were covalently modified with functional monomers to form precursor EstSi. The latter together with coupling reagent KH-570, were grafted onto the surface of SiO₂ nanoparticles before polymerization, to ensure the quantity and quality of imprinted sites on the surface of the covalently attached matrix. The as-synthesized core-shell nanomaterials (SiO₂@MIP2) were then evaluated for selective adsorption of 17¦Ā-estradiol (E2) with Raman spectra as detection method. The results indicate that SiO₂@MIP2 can fast and selectively adsorb E2 from structural analogues, with detection limit of 0.01 ¦Ģmol/l. %K Surface-Imprinting %K Core-Shell Nanoparticle %K Selective Adsorption %K 17< %K i> %K ¦Ā< %K /i> %K -Estradiol %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=88612