%0 Journal Article
%T Cefuroxime-Induced Hepatocellular-Cholestatic Hepatitis with Pancytopenia
%A Wolfgang Kunze
%A Jan-Peter Streidl
%A Thorsten Klemm
%A Juliane Lutze
%J Open Access Library Journal
%V 6
%N 2
%P 1-7
%@ 2333-9721
%D 2019
%I Open Access Library
%R 10.4236/oalib.1105036
%X <div style="text-align:justify;">
	<span style="line-height:1.5;">Drug-induced liver injury is a rare event. We report on a 15-year old girl de-veloping jaundice and a maculopapular rash with pruritus after oral cefuroxime therapy. Liver enzymes as well as total bilirubin and direct bilirubin were elevated. After eliminating other causes of hepatitis, cefuroxime-induced hepatocellular-cholestatic hepatitis with pancytopenia was diagnosed and cefuroxime therapy was stopped. The patient recovered quickly and was discharged without complications. The prognosis of this side-effect of cefuroxime is generally favourable; lethal courses are rare.</span>
</div>
%K Cefuroxime
%K Hepatocellular-Cholestatic Hepatitis
%K Pancytopenia
%K Differential Diagnoses
%U http://www.oalib.com/paper/5301201