%0 Journal Article
%T Prevalence of Polycystic Ovary Syndrome in Nigerian Women with Infertility: A Prospective Study of the Three Assessment Criteria
%A Chinyere Blessing Akpata
%A Patrick Ojeifo Uadia
%A Friday Ebhodaghe Okonofua
%J Open Journal of Obstetrics and Gynecology
%P 1109-1120
%@ 2160-8806
%D 2018
%I Scientific Research Publishing
%R 10.4236/ojog.2018.812112
%X <strong>Background:</strong><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> Polycystic ovarian syndrome (PCOS) is a frequent diagnosis in oligome</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">n</span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">orrheic
and infertile Nigerian women. However, to date there is a paucity of data on
the prevalence of PCOS in Nigerian women. The objective of this study was to
investigate the prevalence of PCOS in a cross-section of women attending
Infertility Clinics in Benin City, Nigeria using the three assessment criteria
namely: the 1990 National Institutes of Health (NIH), the 2003 Rotterdam and
2006 Androgen Excess Society (AES) criteria. </span><b><span style=\"font-family:Verdana;\">Method: </span></b><span style=\"font-family:Verdana;\">Four hundred and
twenty-one consecutive infertile premenopausal women aged 18 - 45</span></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">years
were recruited and evaluated with a proforma that elicited information about
their maternal and reproductive health history. Blood samples were analyzed for
hormone levels using standard immunoassay procedures, while trans-vaginal
ultrasound scan was carried out to determine the presence of ultrasonic
features of PCOS. The control group comprised of eumenorrheics (</span><i><span style=\"font-family:Verdana;\">n</span></i></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">=</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">180). </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> An estimated prevalence of biochemical hyperandrogenism (BHA) was as high as
20.9% (88 women), while 3.6% (15 women) presented with clinical
hyperandrogenism (CHA). Also the prevalence of polycystic ovaries (PCO) was
13.8%. The prevalence of PCOS based on NIH, Rotterdam and AES criteria was
16.9% (71 women), 27.6% (116 women) and 20.7% (87 women) respectively. However,
women with PCOS were significantly younger and had higher
%K Infertility
%K Nigerian Women
%K Oligomenorrhea
%K Polycystic Ovarian Disease
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=87687