%0 Journal Article
%T Effect of Hyoscine Butyl Bromide on the Course of Labour
%A Dauda Deba Barau
%A Eyaofun Teddy Agida
%A Olatunde Onafowokan
%A Francis Olayemi Adebayo
%J Open Journal of Obstetrics and Gynecology
%P 1102-1108
%@ 2160-8806
%D 2018
%I Scientific Research Publishing
%R 10.4236/ojog.2018.812111
%X <strong>Background:</strong><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">Hyoscine</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">butyl</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">bromide
(Buscopan) is being used as an agent for reducing the duration of labour. There
are however conflicting results on the effect of this agent on cervical
dilation.</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">Materials and Methods:</span></b></span></span><span><span><b><span style=\"font-family:&quot;\"> </span></b></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">This was an open label clinical trial of one hundred
and thirty two (132) pregnant women in labour. Women were grouped to receive
either 20</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">mg of hyoscine butyl bromide intramuscularly at the onset of active phase
labour or placebo ˇ°Normal salineˇ±. The main outcome measure was to compare the
duration of first stage labour in the study and control groups as well as
feto-maternal outcomes. Relevant data were collected using a proforma. The data
w</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">ere</span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> analysed using Statistical Package for Social Sciences (SPSS) version
20. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> A total of 132 were randomised and 123 yielded for
analysis. Of these 59 received hyoscine butyl bromide and 64 received placebo.
There was no significant difference in the mean duration of active labour to
second stage between the drug and placebo arms (312.5 versus 305.3 minutes,
respectively,
%K Hyoscine Butyl Bromide
%K Labour
%K Prolonged Labour
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=87682