%0 Journal Article
%T Latent Tuberculosis Infection among Household Contacts of Pulmonary Tuberculosis Cases in Central State, Sudan: Prevalence and Associated Factors
%A Abdulmannan Mohamed Aman
%A Zeidan Abdu Zeidan
%J Journal of Tuberculosis Research
%P 265-275
%@ 2329-8448
%D 2017
%I Scientific Research Publishing
%R 10.4236/jtr.2017.54028
%X <strong>Introduction:</strong> Tuberculosis is a major health problem in developing countries including Sudan. Screening for TB cases through Household contacts (HHCs) investigation is an appropriate strategy to interrupt transmission of TB. <strong>Objectives:</strong> To determine the prevalence tuberculosis infection and risk factors for tuberculosis infection among household contacts in Wadimadani locality, Central State, Sudan, between November 2015 and April 2016. <strong>Methods:</strong> An analytical cross-sectional study conducted. During study period, to confirm TB diagnosis, all suspect contacts were tested through sputum samples, tuberculin skin test or chest X-ray. Structured questionnaire was used to collect socio-demographic and environmental factors. <strong>Results:</strong> One hundred forty six patients of smear-positive pulmonary tuberculosis were included in the study, 657 household contacts were identified and screened. Forty three new TB cases were detected from household contacts, yielding a prevalence of 6.5% (95% confidence interval = 0.05, 0.09) of latent tuberculosis infection (LTBI). Two factors were significantly associated with LTBI among HHCs: duration of contact with a TB patient ¡Ü 4 months (P = 0.03) and the educational status (P = 0.02). <strong>Conclusion:</strong> Screening of HHCs of index case of TB will contribute in early detection and treatment of new cases, and considered as a forward step towards eliminating TB.
%K Tuberculosis
%K Latent Tuberculosis Infection
%K Household Close Contact
%K Central State
%K Sudan
%K Prevalence
%K Risk Factors
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=80968