%0 Journal Article %T Inter-Fraction and Intra-Fraction Variation in the Absorbed-Dose Delivery during Interstitial High Dose Rate Brachytherapy¡ªA Study Using MicroMOSFET <i>In-Vivo</i> Dosimeter %A Seenisamy Ramapandian %A Vivekanandan Nagarajan %A Ashutosh Mukherji %A Parthasarathy Vedasoundaram %A K. S. Reddy %A Vivekanandam Singhavajala %A Vijayaprabhu Neelakandan %J International Journal of Medical Physics,Clinical Engineering and Radiation Oncology %P 445-456 %@ 2168-5444 %D 2017 %I Scientific Research Publishing %R 10.4236/ijmpcero.2017.64040 %X Background: The delivered dose has to be checked and verified with planned dose since precise and accurate dose delivery is essential in Brachytherapy. Sources of uncertainty during Brachytherapy are intra-fraction, inter-fraction and inter-application variations. <i>In-vivo</i> dosimetry is the direct method to monitor the radiation dose delivered to a patient during radiotherapy. In this study, assessment of the inter-fraction and intra-fraction variations in the interstitial Brachytherapy was done with microMOSFET. Aim: To analyze the inter-fraction variations in dose delivery during interstitial HDR Brachytherapy and to compare the measured point dose with the TPS-calculated point dose, intra-fraction variation, using the microMOSFET <i>in-vivo</i> dosimeter. Materials and Methods: From May 2014 to February 2016, 22 patients with Head and Neck cancers and 8 patients with Soft-Tissue Sarcomas (STS) were selected for this study. All these patients underwent CT imaging more than 24 hours after the application. Brachyvision 3DTPS and GammaMed Plus iX HDR unit were used for treatments. MicroMOSFET <i>in-vivo</i> dosimeter after calibration was used for the measurements of dose inside the treated volume. Intra & %K MicroMOSFET %K Interstitial Brachytherapy %K MicroMOSFET in Brachytherapy %K < %K i> %K In-Vivo< %K /i> %K Dosimetry in Brachytherapy %K Dose Verification in Brachytherapy %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=80687