%0 Journal Article
%T Clinicopathological Pattern of Basal Cell Carcinoma among Sudanese Patients
%A Tasneem Mohammed Elshiekh Sulieman
%A Nazik Elmalaika Obaid Seid Ahmed Husain
%J Open Journal of Pathology
%P 67-79
%@ 2164-6783
%D 2017
%I Scientific Research Publishing
%R 10.4236/ojpathology.2017.74007
%X Background: Basal cell carcinoma (BCC) is a frequently diagnosed skin cancer with variable histopathological types. BCC was not widely studied in Sudan as it is in the Caucasian population. Objectives: To appraise the clinical and histopathological aspects of BCC of the skin in Sudan. Materials and methods: A retrospective descriptive analysis of 84 histologically diagnosed BCC specimens seen at three hospitals in four-year duration were reviewed and classified into histological variants according to the WHO classification 2006. Data were analyzed using Statistical Package for the Social Sciences, version 23.0. Results: The mean age (”ĄSD) of the study participants was 56 (”Ą1.75) years, ranging from 20 to 92 years and 63.1% were females (Female to male ratio 1.7:1). The most common incidence was among the age group 51 - 60 years. The face was the primary tumor site in 89.3% with a predilection for the nasal area (31% of those in the face), followed by the trunk (6%). Out of the total, 54.8% were histologically categorized as nodular/solid, while infiltrative accounts for 11.9% followed by the superficial type (8.3%). Surgical margins were involved in 34.5% of cases and peri-neural invasion was seen in 3.6% of cases, mostly were of the infiltrative variant. Conclusion: BCC in Sudan is commonly present in the head as solid nodular histopathological variant which is correlated with worldwide distribution but has slightly younger age and female predominance; thus further studies are needed to assess risk factors in Sudanese patients and improve approaches for earlier diagnosis and better management.
%K Basal Cell Carcinoma
%K Skin
%K Histologic Pattern
%K WHO Classification
%K Sudan
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=78969