%0 Journal Article %T Novel Wavelet-Based Segmentation of Prostate CBCT Images with Implanted Calypso Transponders %A Yingxia Liu %A Ziad Saleh %A Yulin Song %A Maria Chan %A Xiang Li %A Chengyu Shi %A Xin Qian %A Xiaoli Tang %J International Journal of Medical Physics,Clinical Engineering and Radiation Oncology %P 336-343 %@ 2168-5444 %D 2017 %I Scientific Research Publishing %R 10.4236/ijmpcero.2017.63030 %X Segmentation of prostate Cone Beam CT (CBCT) images is an essential step towards real-time adaptive radiotherapy (ART). It is challenging for Calypso patients, as more artifacts generated by the beacon transponders are present on the images. We herein propose a novel wavelet-based segmentation algorithm for rectum, bladder, and prostate of CBCT images with implanted Calypso transponders. For a given CBCT, a Moving Window-Based Double Haar (MWDH) transformation is applied first to obtain the wavelet coefficients. Based on a user defined point in the object of interest, a cluster algorithm based adaptive thresholding is applied to the low frequency components of the wavelet coefficients, and a Lee filter theory based adaptive thresholding is applied on the high frequency components. For the next step, the wavelet reconstruction is applied to the thresholded wavelet coefficients. A binary (segmented) image of the object of interest is therefore obtained. 5 hypofractionated Calypso prostate patients with daily CBCT were studied. DICE, Sensitivity, Inclusiveness and ΔV were used to evaluate the segmentation result. %K CBCT %K Prostate Segmentation %K Wavelets %K MWDH %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=78803