%0 Journal Article
%T Model of Long-Term Vitamin A Deficiency in the Mammary Gland of Virgin Rats
%A Miriam Ester Vasquez Gomez
%A Silvia Varas
%A Maria Sofia Gimenez
%J Open Access Library Journal
%V 4
%N 9
%P 1-14
%@ 2333-9721
%D 2017
%I Open Access Library
%R 10.4236/oalib.1103887
%X <div style="text-align:justify;">
	<span style="line-height:1.5;">Deficiency in vitamin A is an evil in underdeveloped
countries where the minimum recommended intake is not achieved. This may have
long-term implications on the health of the population. For this reason, it
would be very useful to achieve an animal model where the different
implications of this deficiency can be observed. This could lead to the
formulation of future nutrition politics. The levels of retinoic acid and intermediary</span><span style="line-height:1.5;"> of the vitamin A pathway were studied;
The levels of retinoic acid and intermediary of the vitamin A pathway (CRBP-1
and RAR</span><i style="line-height:1.5;">¦Á</i><span style="line-height:1.5;">) were studied. There was a
decrease in the values of retinoic acid main indicator of deficiency of this
vitamin in serum, liver and mammary gland and variation in expression of CRBP-1
and RAR</span><i style="line-height:1.5;">¦Á</i><span style="line-height:1.5;"> mRNA in mammary gland. This
model provides a tool for the study of the metabolism of vitamin A and its
effects in different organs and especially in virgin mammary gland, where a deficiency
is achieved despite being in a state of latency.</span>
</div>
%K Retinoic Acid
%K Nutrition
%K CRBP-1
%K RAR¦Á
%U http://www.oalib.com/paper/5289433