%0 Journal Article
%T A Novel Friedel-Crafts Acylation Reaction of Anisole for Production of 4-Methoxyacetophenone with High Selectivity and Sufficient Reusability of Mordenite Zeolite Catalyst
%A Makoto Makihara
%A Kenichi Komura
%J Green and Sustainable Chemistry
%P 185-192
%@ 2160-696X
%D 2017
%I Scientific Research Publishing
%R 10.4236/gsc.2017.73014
%X Zeolite catalyzed Friedel-Crafts reactions were examined using acetic anhydride as an acetylating agent and an acetic acid as a solvent. It revealed that the reaction of anisole smoothly occurred quantitatively for 3 h using mordenite zeolite with SiO<sub>2</sub>/Al<sub>2</sub>O<sub>3</sub> = 200, and with SiO<sub>2</sub>/Al<sub>2</sub>O<sub>3</sub> = 110, the increasing of Br&oslash;nsted acidity allowed to completely react within 2 h. Furthermore the selectivity of 4-methoxyacetophenone (4-MA) among the isomers was found to be quantitative, no by-products and/or isomers were not detectable. With the excellent recyclability and reusability, the mordenite zeolite exhibited at least 30 times quantitatively both conversion of anisole and selectivity of 4-MA. The mordenite catalysts of fresh and the used after 30 times were characterized. This opportunity obviously indicates the sufficient shape selective catalyst of mordenite zeolite and gives a green synthetic tool for heterogeneous acylation reaction.
%K Zeolite
%K Friedel-Crafts
%K Acylation
%K Mordenite
%K Shape Selectivity
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=77762