%0 Journal Article %T Discrete Differential Geometry and the Structural Study of Protein Complexes %A Naoto Morikawa %J Open Journal of Discrete Mathematics %P 148-164 %@ 2161-7643 %D 2017 %I Scientific Research Publishing %R 10.4236/ojdm.2017.73014 %X This paper proposes a novel four-dimensional approach to the structural study of protein complexes. In the approach, the surface of a protein molecule is to be described using the intersection of a pair of four-dimensional triangular cones (with multiple top vertexes). As a mathematical toy model of protein complexes, we consider complexes of closed trajectories of n-simplices (n=2,3,4...), where the design problem of protein complexes corresponds to an extended version of the Hamiltonian cycle problem. The problem is to find ¡°a set of¡± closed trajectories of n-simplices which fills the n-dimensional region defined by a given pair of n+1 -dimensional triangular cones. Here we give a solution to the extended Hamiltonian cycle problem in the case of n=2 using the discrete differential geometry of triangles (i.e., 2-simplices). %K Discrete Differential Geometry %K < %K i> %K n< %K /i> %K -Simplices %K Hamiltonian Cycle Problem %K Protein Complexes %K Vector Bundle %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=77508