%0 Journal Article
%T Intracranial Intermediate-Grade Melanocytic Neoplasm: Case Report Associated with Nevus of Ota
%A Dorothy Sze Wing Hung
%A Calvin Hoi Kwan Mak
%A Fung Ching Cheung
%J Open Journal of Modern Neurosurgery
%P 65-74
%@ 2163-0585
%D 2017
%I Scientific Research Publishing
%R 10.4236/ojmn.2017.73008
%X Melanocytic lesions of the CNS are rare tumours
originating from melanocytes that are present in the leptomeninges. They
consist of a spectrum of pigmented </span><span style=\"font-family:Verdana;\">tumours ranging from melanocytoma to
melanoma. A small group of these tumours have histopathological features
between those of a benign melanocytoma and a malignant melanoma; these present
as intermediate grade melanocytic neoplasms. Naevus of Ota is a blue
hyperpigmented dermal lesion characterized by increased number of melanocytes
in the distribution of ophthalmic and maxillary divisions of the trigeminal
nerve. The association of an intracranial intermediate-grade melanocytic
neoplasm with a nevus of Ota is extremely rare, with only 2 cases reported in
the literature to date. As a result, their behavior and progression are still
poorly understood. We present the first case of a familial naevus of Ota
associated with intermediate-grade melanocytic neoplasm.
%K Melanocytic Neoplasm
%K Leptomeninges
%K Nevus of Ota
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=77422