%0 Journal Article
%T A Case Report of Multiple Cylindroma with Immunohistochemical Features
%A Naoki Watanabe
%A Kana Kawase
%A Chisato Tawada
%A Kazufumi Yoneda
%A Kuniaki Hirai
%A Ayumi Niwa
%A Takuji Tanaka
%J Open Journal of Pathology
%P 134-139
%@ 2164-6783
%D 2016
%I Scientific Research Publishing
%R 10.4236/ojpathology.2016.63016
%X Cylindroma is a benign skin appendageal
tumor arising from pluripotent stem cells in the follicle. Multiple cylindroma
typically occurs as a component of Brooke-Spiegler syndrome or as the only skin
lesion of familial cylindromatosis. We herein report an unusual case of
multiple cylindroma involving the trunk without any other features of
Brooke-Spiegler syndrome and no family history supporting the possibility of
familial cylindromatosis. Immunohistochemical features of CYLD and NF-¦ĘB, which
are involved in the pathogenesis of cylindroma, in the tumors are also
presented.
%K Multiple Cylindroma
%K Immunohistochemistry
%K CYLD
%K NF-¦ĘB
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=67836