%0 Journal Article
%T Prevalence of Class 1 Integron, Resistance Gene Cassettes and Antimicrobial Susceptibility Profiles among Isolates of <i>Pseudomonas aeruginosa</i> in Iran
%A Maryam Mirahsani
%A Ahmad Khorshidi
%A Rezvan Moniri
%A Hamid Reza Gilasi
%J Open Journal of Medical Microbiology
%P 87-96
%@ 2165-3380
%D 2016
%I Scientific Research Publishing
%R 10.4236/ojmm.2016.62012
%X <i>Pseudomonas aeruginosa</i> is one of the most important opportunistic human pathogens worldwide. High prevalence of Multi Drug Resistant <i>P. aeruginosa</i> (MDRPa) in Iran is a serious problem for antimicrobial therapy. Several studies have reported the MDRPa in Europe and Asia. Due to the use of broad-spectrum antibiotics, bacterial resistance is increasing in Iran, located in Middle East. The present cross-sectional study was designed to investigate the prevalence of class1 integron, resistance gene cassettes and antimicrobial susceptibility profiles among isolates of <i>P. aeruginosa</i> in Al-Zahra Hospital, Isfahan City, central part of Iran from Jan-Sep 2014. The aim of this study was to determine the antimicrobial susceptibility, the prevalence of Class1 integron, resistance gene a measuring in Iran. A total of 231 <i>P. aeruginosa</i> isolates were collected from clinical specimens including urine (50.6%), tracheal tube (25.5%), wound (13.4%), blood (6.1%), catheter (2.2%), cerebrospinal fluid (1.7%) and sputum (0.4%) isolates from hospitalized patients (mean age: 50.27 ¡À 24.12 years).The majority of patients (68%) were male. Isolates were collected from different parts of the hospital as follows: ICU, Internal Medicine, Emergency care, Pediatrics, Nephrology, Transplant Center, General surgery and Infectious. Revealed data show a high rate of MDR <i>P. aeruginosa</i> isolates in the studied area; also, the result signifies the spread of aadA6 among clinical isolates in hospitalized patients.
%K &lt
%K i&gt
%K Pseudomonas aeruginosa&lt
%K /i&gt
%K Resistance Gene Cassettes
%K Antibiotic Susceptibility
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=67688