%0 Journal Article
%T NF-КBP65和BCL-2蛋白在多形性腺瘤中的表达<br>The Expression of NF-КBP65 and BCL-2 Protein in Pleomorphic Adenoma
%A 陈昌晖
%A 肖维华
%J Hans Journal of Biomedicine
%P 1-5
%@ 2161-8984
%D 2016
%I Hans Publishing
%R 10.12677/HJBM.2016.61001
%X <div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">目的：检测NF-КBP65与BCL-2蛋白在多形性腺瘤及瘤旁正常涎腺组织中的表达情况，探讨NF-КBP65与BCL-2蛋白在多形性腺瘤的表达意义。方法：采用免疫组织化学S-P法检测20例涎腺多形性腺瘤组织石蜡标本中NF-КBP65与BCL-2蛋白表达水平，以瘤旁正常涎腺组织作为对照，进行组内及组间比较。结果：多形性腺瘤和瘤旁正常涎腺组织中NF-КBP65表达的阳性率分别为55%和10.0%，差异有统计学意义(P&lt;0.05)；BCL-2表达的阳性率分别为35%和10.0%，差异有统计学意义(P&lt;0.05)。结论： NF-КBP65 和BCL-2的协同作用可能对多形性腺瘤的发生、发展起重要作用。<br />
Objective: To detect the expression and discuss the expression meaning of NF-КBP65 and BCL-2 protein in pleomorphic adenoma. Methods: The expression of NF-КBP65 and BCL-2 protein in pa-raffin embedded specimens of pleomorphic adenoma and adjacent normal salivary gland tissue of 20 cases was detected using immunohistochemical S-P method. Results: The positive rates of NF-КBP65 expression in pleomorphic adenoma and adjacent normal salivary gland tissue were&nbsp; 55% and 10%, and the positive rates of BCL-2 expression were 35% and 10% respectively. The differences of NF-КBP65 and BCL-2 expression in pleomorphic adenoma and tumor adjacent normal salivary gland tissue were statistically significant (P &lt; 0.05). Conclusion: NF-КBP65 and BCL-2 may play an important role in pleomorphic adenoma occurrence and development.</span><span style=\"line-height:1.5;\"></span> 
</div>
%K 多形性腺瘤，NF-КBP65，BCL-2，免疫组化<br>Pleomorphic Adenoma
%K NF-КBP65
%K BCL-2
%K Immunohistochemical
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=16804