%0 Journal Article
%T Herpes Simplex Virus 1, Cytomegalovirus and Epstein Barr Virus Detection in Patients with Chronic and Aggressive Periodontitis
%A Harold H. Hern¨¢ndez
%A Andre¨ªna S. Fernandes
%A Laura A. Escalona
%A Mar¨ªa Correnti
%J Open Access Library Journal
%V 3
%N 3
%P 1-9
%@ 2333-9721
%D 2016
%I Open Access Library
%R 10.4236/oalib.1102557
%X Recent investigations suggest that the viruses of the family
Herpesviridae are associated with periodontal disease, demonstrating a possible
association with the presence of Human Cytomegalovirus (HCMV), Herpes Simplex
Virus 1 (HSV-1) and Epstein Barr Virus (EBV) in periodontal tissues. Aim: To
analyze the association between the presence of HSV-1, HCMV and EBV in patients
with chronic or aggressive periodontitis. Methods: Crevicular fluid samples
were collected from 11 patients with aggressive periodontitis (AgP), 11 with
chronic periodontitis (CP) and 11 healthy control subjects (CG). The following
clinical parameters were measured: plaque index (PI), bleeding on probing
(BOP), probing depths (PD) and clinical attachment loss (CAL). Viral detection
was performed by PCR for HSV-1, HCMV and EBV. Results: HCMV was detected in
27.3% of AgP patients but not detected in CP and healthy subjects; HSV-1 in
27.3% of AgP and CP group and in 9.1% of CG. EBV-1 was detected in 18.2% of CP
patients and 9.1% of the CG. HCMV and HSV-1 coinfection was detected in 18.8%
of AgP patients and 9.09% of viral coinfection between HSV-1 and VEB, within
the CP group. The AgP group exhibited the higher values for all clinical parameters
evaluated, respect to the CP and control group. Conclusion: The presence of
HCMV may be related to periodontal disease, specifically in cases of AgP, and
it may play a synergistic role with other infectious agents from the oral
cavity associated with the development of periodontitis.
%K Periodontitis
%K Gingival Crevicular Fluid
%K Cytomegalovirus
%K Herpes Simplex Virus
%K Epstein Barr Virus
%U http://www.oalib.com/paper/5264276