%0 Journal Article
%T 自体造血干细胞移植治疗侵袭性NK/T细胞淋巴瘤
%A 牛挺
%A 陈心传
%A 薛红利
%A 李建军
%A 刘志刚
%A 刘霆
%J 华西医学
%P 1763-1766
%D 2011
%X 【】　目的　探讨自体造血干细胞移植（autologoushematopoieticstemcelltransplantation，auto-HSCT）治疗侵袭性NK/T细胞淋巴瘤的疗效。　方法　对我科2005年1月16日收治的1例侵袭性NK/T细胞淋巴瘤患者的造血干细胞移植和随访资料进行回顾性分析，并复习国内外相关文献。　结果　患者为37岁女性，诊断结外鼻型NK/T细胞淋巴瘤，系统性，经CHOAP和ICE方案化学疗法、手术、局部放射治疗控制病情良好后，采集自体骨髓造血干细胞，行auto-HSCT，预处理方案为全身放射治疗+ECy；移植+29d造血功能即顺利重建；移植后密切随访，患者一直处于完全缓解，至今已存活67个月。　结论　auto-HSCT治疗侵袭性NK/T细胞淋巴瘤疗效肯定、可靠。【Abstract】　Objective　Toexplorethetherapeuticeffectofautologoushematopoieticstemcelltransplantation(auto-HSCT)onaggressiveNK/Tlymphoma.　Methods　TheclinicaldataofonepatientwithaggressiveNK/TlymphomadiagnosedinJanuary2005wereretrospectivelyanalyzed,andtherelevantdomesticliteratureswereanalyzed.　Results　Thisthirty-seven-year-oldfemalepatienthadgooddiseasecontrolafterundergoingchemotherapywithCHOAPandICEregimens,surgery,andlocoregionalradiotherapy.Afterthat,shehadbeencollectedenoughbonemarrow-derivedhematopoieticstemcells,thenunderwentauto-HSCTwiththesecells.TheconditioningregimenwasTBIplusECy.Onthe+29thdayaftertransplantation,thehematopoieticreconstructionwassuccessful.Duringthefollow-upperiod,thepatientwasincompleteremissionstatusallalongandherdisease-freesurvival(DFS)was67months.　Conclusion　Auto-HSCTiseffectiveonaggressiveNK/Tlymphoma.
%K 侵袭性NK/T细胞淋巴瘤
%K 自体造血干细胞移植
%K 治疗
%U http://www.hxyxqk.com.cn/oa/DArticle.aspx?type=view&id=201112002