%0 Journal Article
%T 朱砂莲中毒致急性肾功能衰竭二例
%A 刘晓霞
%A 田茂露
%A 胡章学
%A 舒英
%A 黄思念
%A 张秀辉
%J 华西医学
%P 18-20
%D 2012
%R CNKI:51-1356/R.20120115.1541.005
%X 目的　分析朱砂莲中毒导致急性肾功能衰竭临床表现、肾脏病理学及相关文献复习。方法　2007年3月－9月收治朱砂莲中毒急性肾功能衰竭2例，分析临床表现及肾脏病理损害。结果　朱砂莲急性中毒易致急性肾功能衰竭，危及生命；其主要损害肾小管间质，表现为急性肾小管重度损伤，无炎性细胞浸润，而肾小球几乎无病变。结论　朱砂莲为我国常使用中药，主要成分为马兜铃酸，易致马兜铃酸肾病，须提高对该病认识，规范使用中草药，避免药物性所致肾损害。Objective　Toanalyzetheclinicalandpathologicalmanifestationsofkidneyinpatientswithciliatenerveknotweedroot-inducedacuterenalfailure.Methods　Twopatientswhowereadmittedintoourhospitalforacuterenalfailurecausedbyover-doseciliatenerveknotweedrootfromMarchtoSeptemberin2007wereincludedinthisstudy.Weanalyzedtheclinicalandpathologicalmanifestationsoftheirkidneys.Results　Over-doseciliatenerveknotweedrootcouldinduceacuterenalfailure,eventhreatenlife.Thepathologyofkidneyischaracterizedbyseveretubularinjury,ratherthanglomerulusdamage,withoutcellinfiltration.Conclusions　Ciliatenerveknotweedrootisoneofthefrequently-usedtraditionalChinesemedicinesinourcountry,whichcaneasilyresultinaristolochincacidnephropathy.Weshouldrecognizetheimportanceofthisdiseaseandavoidusingnephrotoxicdrugs.
%K 朱砂莲
%K 马兜铃酸肾病
%K 急性肾功能衰竭
%U http://www.hxyxqk.com.cn/oa/DArticle.aspx?type=view&id=201201005