%0 Journal Article %T 替米沙坦对高血压伴阵发性心房颤动患者房颤复发及C反应蛋白的影响 %A 王心群 %A 邓学军 %J 华西医学 %P 1592-1593 %D 2010 %X 【】目的观察替米沙坦对高血压伴阵发性心房颤动患者房颤复发及对左心房内径(LAD)、血清C反应蛋白(HsCRP)的影响。方法2007年6月-2008年12月阵发性房颤患者42例,随机分为替米沙坦组和常规治疗组各21例,分别于治疗前、治疗后12个月测定LAD、HsCRP水平,并随访治疗后12个月时房颤复发次数。结果替米沙坦组房颤复发次数及LAD、HsCRP水平均低于常规治疗组,两组比较,有统计学意义(P<0.05)。结论替米沙坦能抑制高血压伴阵发性房颤患者的左房重构,降低HsCRP水平,减少房颤复发。?【Abstract】ObjectiveToexploretheeffectsofTelmisartanonrecurrenceofparoxysmalatrialfibrillation(PAF),leftatrialdirection(LAD)andserumlevelsofhighsensitivityCreactionprotein(HsCRP)inpatientswithhypertensioncombinedwithparoxysmatrialfibrillation.MethodsAtotalof42PAFpatientsfromJune2007toDecember2008wererandomlydividedintoTelmisartangroupandroutinetreatmentgroup.Beforethetreatmentand12monthsafterthetreatment,LADandHsCRPweredetected,andtherecurrencetimesofatrialfibrillationwerecounted12monthsafterthetreatment.ResultsTherecurrencetimesofatrialfibrillation,andthelevelsofLADandHsCRPweresignificantlowerinTelmisartangroupthanthatintheroutinetreatmentgroup(P<0.05).ConclusionTelmisartancanreducetherecurrenceofPAFandthelevelsofLADandHsCRP. %K 替米沙坦 %K 高敏C反应蛋白 %K 心房颤动 %U http://www.hxyxqk.com.cn/oa/DArticle.aspx?type=view&id=201009002