%0 Journal Article %T 儿童传染性单核细胞增多症临床特征分析 %A 许玉霞 %A 廖先华 %A 易志刚 %A 刘增荣 %J 华西医学 %P 1270-1272 %D 2010 %X 【】目的探讨儿童传染性单核细胞增多症(IM)的临床特点。方法回顾性分析2005年8月-2009年8月收治的151例IM患儿的症状、体征、实验室检查及治疗效果。结果IM临床表现以发热、咽峡炎、肝脾和淋巴结肿大最常见,鼻塞、眼睑浮肿也是重要体征。外周血出现异型淋巴细胞及EBV-IgM抗体检测可帮助确诊。更昔洛韦治疗IM效果确切。结论应重视IM临床特点,有助于早期诊断并提高确诊率,应用更昔洛韦治疗值得推广。【Abstract】ObjectiveToinvestigatetheclinicalfeaturesofinfectiousmononucleosis(IM)inchildren.MethodsAtotalof151childrenwithinfectiousmononucleosisadmittedfromAugust2005toAugust2009werereviewed.Thesymptoms,signs,laboratorytests,andtreatmentofinfectiousmononucleosiswereanalyzed.ResultsFever,angina,hepatomegaly,splenomegaly,andswollenlymphnodeswerethemostcommonclinicalmanifestationsofIM.Nasalcongestionandeyelidedemawerealsotwoimportantsigns.AtypicallymphocytesinperipheralbloodandEBVantibody(VCA-IgM)couldhelpconfirmthediagnosis.Theantiviraltreatmentwithganciclovirwaseffectiveforinfectiousmononucleosis.ConclusionClinicalfeaturesofinfectiousmononucleosisarehelpfultothediagnosis.Treatmentwithganciclovirshouldbepromoted. %K 传染性单核细胞增多症 %K 临床特点 %K 更昔洛韦 %U http://www.hxyxqk.com.cn/oa/DArticle.aspx?type=view&id=201007029