%0 Journal Article
%T 腰池置管脑脊液外引流治疗颅内感染临床分析
%A 钟琪
%A 王伟
%A 李鹏
%A 李国平
%A 王兴
%A 任海波
%J 华西医学
%P 359-361
%D 2011
%X 　方法　2008年9月-2009年11月，将20例颅脑外伤后颅内感染患者分为脑脊液外引流组和抗生素组各10例，外引流组进行持续腰池置管脑脊液外引流，定期取引流脑脊液进行常规和生化检查；抗生素组采用静脉抗生素治疗。对两组颅内感染情况进行对比分析。　结果　外引流组经持续腰池置管脑脊液外引流治疗后，颅内感染临床症状明显缓解，脑脊液有核细胞数和脑脊液微量蛋白含量显著降低、脑脊液葡萄糖和氯化物浓度升高（P<0.05）。治疗10d后，外引流组体温、脑脊液有核细胞数、脑脊液微量蛋白含量、脑脊液葡萄糖和氯化物浓度的改善程度明显优于抗生素组（P<0.05）。　结论　持续腰池置管脑脊液外引流治疗颅内感染具有安全性高、操作简便、观察颅内感染情况方便的优点，可作为颅内感染可靠治疗手段。【Abstract】　Objective　Toobservetheefficacyofcontinuouslumbardrainageofcerebrospinalfluidviaalumbarcatheterintreatingintracranialinfection.　Methods　FromSeptember2008toNovember2009,20patientswithintracranialinfectionafterheadtraumawereenrolledinthisstudy.Tenofthem,classifiedastheexternaldrainagegroup,sustainedcontinuousexternallumbardrainageofcerebrospinalfluid.Thecerebrospinalfluidwasobtainedregularlyforroutineandbiochemicalexamination.Theother10patientswerecategorizedastheantibioticsgroup.Theyonlyacceptedintravenousantibiotictherapy.　Results　Forthepatientsintheexternaldrainagegoup,aftercontinuousexternallumbardrainageofcerebrospinalfluid,theirclinicalsymptomsofintracranialinfectionweresignificantlyalleviatedandthenumberofnucleatedcellsandproteincontentinthecerebrospinalfluiddecreasedsignificantly,whiletheglucoseandchlorideconcentrationsincreasedsignificantly(P<0.05).After10daysoftreatment,thepatientsintheexternaldrainagegroupweresuperiortothoseintheantibioticsgroupinimprovementofthebodytemperature,thenumberofnucleatedcellsandproteincontent,glucoseandchlorideconcentrationsinthecerebrospinalfluid(P<0.05).　Conclusion　Continuouslumbardrainageofcerebrospinalfluidissimpleandsafe.Itprovidesaneasywayofmonitoringtheintracranialinfectionandcanbeareliabletreatment.
%K 持续腰池置管
%K 脑脊液外引流
%K 颅内感染
%U http://www.hxyxqk.com.cn/oa/DArticle.aspx?type=view&id=201103012