%0 Journal Article %T Proliferative Activity (Ki-67 Expression) and Outcome in High Grade Osteosarcoma: A Study of 27 Cases %A Roland Jong %A Aileen M. Davis %A Maria G. Mendes %A Jay S. Wunder %A Robert S. Bell %A Rita Kandel %J Sarcoma %D 2000 %I Hindawi Publishing Corporation %R 10.1155/s1357714x00000086 %X Purpose. Although pre-operative chemotherapy has improved the prognosis for individuals with osteosarcoma, approximately 40% of patients will die of their disease.The aim of this study was to quantitate proliferative activity in high grade osteosarcomas and to determine whether proliferation is a prognostic factor. %U http://www.hindawi.com/journals/srcm/2000/232410/abs/