%0 Journal Article
%T Primary Meningeal Rhabdomyosarcoma
%A Manisha Palta
%A Richard F. Riedel
%A James J. Vredenburgh
%A Thomas J. Cummings
%A Scott Green
%A Zheng Chang
%A John P. Kirkpatrick
%J Sarcoma
%D 2011
%I Hindawi Publishing Corporation
%R 10.1155/2011/312802
%X Primary meningeal rhabdomyosarcoma is a rare primary brain malignancy, with scant case reports. While most reports of primary intracranial rhabdomyosarcoma occur in pediatric patients, a handful of cases in adult patients have been reported in the medical literature. We report the case of a 44-year-old male who developed primary meningeal rhabdomyosarcoma. After developing episodes of right lower extremity weakness, word finding difficulty, and headaches, a brain magnetic resonance imaging (MRI) demonstrated a vertex lesion with radiographic appearance of a meningeal-derived tumor. Subtotal surgical resection was performed due to sagittal sinus invasion and initial pathology was interpreted as an anaplastic meningioma. Re-review of pathology demonstrated rhabdomyosarcoma negative for alveolar translocation t(2;13). Staging studies revealed no evidence of disseminated disease. He was treated with stereotactic radiotherapy with concurrent temozolamide to be followed by vincristine, actinomycin-D, and cyclophosphamide (VAC) systemic therapy.
%U http://www.hindawi.com/journals/srcm/2011/312802/