%0 Journal Article
%T QTL Mapping of a High Protein Digestibility Trait in Sorghum bicolor
%A Jennifer A. Winn
%A R. Esten Mason
%A Adriana L. Robbins
%A William L. Rooney
%A Dirk B. Hays
%J International Journal of Plant Genomics
%D 2009
%I Hindawi Publishing Corporation
%R 10.1155/2009/471853
%X Compared with other cereal grains, Sorghum bicolor shows lower protein digestibility. The low digestibility is thought to result from disulfide cross linking in the - and -kafirins. In contrast, the single recessive high digestibility/high lysine content (HD) mutation which confers greater grain digestibility exists in sorghum that is thought to result from reduced accumulation of -kafirin that allows greater access to the high digestible -kafarin fraction. In an effort to both clearly define the molecular basis for the HD trait and develop tools to improve the introgression of this difficult-to-screen trait, this study focuses on mapping the QTLs linked to this trait. While the HD trait has been defined as a single recessive gene, our results uncovered that two major QTLs on chromosome 1 are associated with protein digestibility—one QTL (locus 1 from the HD parent) unfavorably affects digestibility and one QTL (locus 2 from the HD parent) only 20 cM away favorably affects digestibility. A contrast analysis between genotypic groups at these two loci shows that a higher level of protein digestibility may be obtained when this linkage in repulsion is broken and favorable alleles are allowed to recombine.
%U http://www.hindawi.com/journals/ijpg/2009/471853/