%0 Journal Article
%T SiO2-Cu2O£ºAnefficientandrecyclableheterogeneouscatalystforN-benzylationofprimaryandsecondaryamines
%A Manjulla Gupta
%A Satya Paul
%A Rajive Gupta
%J ´ß»¯Ñ§±¨
%P 444-450
%D 2014
%R 10.1016/S1872-2067(14)60009-7
%X £¿Amild,effective,andselectiveprocedureisreportedforthemonoN-benzylationandN,N-dibenzylationofprimaryaminesaswellasmonoN-benzylationofsecondaryaminesusingsilica-supportedcopper(I)oxideinwater.Thesilica-supportedCu2OwasgeneratedinsitubythereactionofFehlingsolutionandglucoseat100¡æontoactivatedsilica.Thecatalystwasfiltered,washedwithwater,andoven-dried,andwascharacterizedbyFouriertransforminfraredspectroscopy,thermogravimetricanalysis,scanningelectronmicroscopy,transmissionelectronmicroscopy,andatomicabsorptionspectroscopy.ThepreparedCu2O-SiO2wasfoundtobethermallystableupto325¡æ.Thecopperwasuniformlydistributedontothesurfaceofthesilica,andthemeanparticlediameterwas7nm.ThecatalystservedasaselectiveheterogenouscatalystfortheN-benzylationofprimaryandsecondaryamines.Thecatalystisrecyclableandwasusedeffectivelyuptofifthrunwithoutasignificantlossofcatalyticactivity.Variousreactionsolventsincludingwater,acetonitrile,andtoluenewerescreenedforN-benzylationofamines,andthesuccessoftheaqueoussystemhighlightsthelowenvironmentalimpactoftheprocedure.
%K Silicasupportedcopper(I)oxide
%K Benzylation
%K Substitutedamine
%K Recyclability
%K Heterogeneouscatalysis
%U http://www.chxb.cn/CN/abstract/abstract21247.shtml