%0 Journal Article
%T CobaltNanoparticlesPromotedHighlyEfficientOnePotFour-ComponentSynthesisof1,4-DihydropyridinesunderSolvent-FreeConditions
%A Javad SAFARI
%A Sayed Hossein BANITABA
%A Shiva DEHGHAN KHALILI
%J ´ß»¯Ñ§±¨
%P 1850-1855
%D 2011
%R 10.1016/S1872-2067(10)60295-1
%X £¿AstraightforwardandgeneralmethodhasbeendevelopedforthesynthesisofC5-unsubstitiuted1,4-dihydropyridinesbyareactionusingdimedone,acetophenone,aromaticaldehydes,andammoniumacetateinthepresenceofacatalyticamountofConanoparticlesasaheterogeneousandeco-friendlycatalystwithhighcatalyticactivityatroomtemperatureundersolvent-freeconditions.Thiscatalystiseasilyseparatedbymagneticdevicesandcanbereusedwithoutanyapparentlossofactivityforthereaction.Inaddition,itisveryinterestingthatwhenusingConanoparticlesasacatalyst,spatially-hinderedaldehydessuchas2-methoxy-,2-fluoro-,and2-chloro-aldehydesaresuitableforthisreaction.
%K cobaltnanoparticle
%K 1
%K 4-dihydropyridine
%K four-componentcondensation
%K heterogeneoucatalyst
%K magneticallyseparablecatalyst
%U http://www.chxb.cn/CN/abstract/abstract20579.shtml