%0 Journal Article
%T Synthesisof2-SubstitutedBenzimidazolesand1,5-DisubstitutedBenzodiazepinesonAluminaandZirconiaCatalysts
%A M. REKHA
%A A. HAMZA
%A B. R. VENUGOPAL
%A N. NAGARAJU
%J ´ß»¯Ñ§±¨
%P 438-446
%D 2012
%R 10.1016/S1872-2067(11)60338-0
%X £¿Inthisstudy,alumina,zirconia,manganeseoxide/alumina,andmanganeseoxide/zirconiahavebeeninvestigatedfortheircatalyticactivityinthecondensationreactionbetweeno-phenylenediamineandanaldehydeoraketonetosynthesise2-substitutedbenzimidazolesand1,5-disubstitutedbenzodiazepinesrespectively.Surfacearea,surfaceacidity,andmorphologyofthecatalystshavebeenanalysedandcorrelatedwiththeircatalyticactivity.Theisolatedyieldsof2-substitutedbenzimidazolesand1,5-disubstitutedbenzodiazepinesareintherangeof30%to95%.Agoodcorrelationbetweentheamountofsurfaceacidsitesaswellasthesurfacemorphologyofthecatalystsandthecatalyticactivityhasbeenobserved.Thismethodhasbeenfoundtobesimpleandeconomical.Thesolidsupportscouldberegeneratedandreusedwithoutmuchlossintheiractivity.Further,thesolidsupportshavebeenalsofoundtobeeffectiveasgeneralcatalystsinthecondensationofo-phenylenediaminewithothersubstitutedaldehydesandketones.
%K 2-substitutedbenzimidazoles
%K 1
%K 5-disubstitutedbenzodiazepines
%K manganeseoxide
%K alumina
%K zirconia
%U http://www.chxb.cn/CN/abstract/abstract20666.shtml