%0 Journal Article
%T A time-dependent Poisson random field model for polymorphism within and between two related biological species
%A Amei Amei
%A Stanley Sawyer
%J Quantitative Biology
%D 2010
%I arXiv
%R 10.1214/09-AAP668
%X We derive a Poisson random field model for population site polymorphisms differences within and between two species that share a relatively recent common ancestor. The model can be either equilibrium or time inhomogeneous. We first consider a random field of Markov chains that describes the fate of a set of individual mutations. This field is approximated by a Poisson random field from which we can make inferences about the amounts of mutation and selection that have occurred in the history of observed aligned DNA sequences.
%U http://arxiv.org/abs/1011.1724v1