%0 Journal Article %T Switching rates of multi-step reactions %A Carlos Escudero %A Alex Kamenev %J Quantitative Biology %D 2008 %I arXiv %R 10.1103/PhysRevE.79.041149 %X We consider a switching rate of a meta-stable reaction scheme, which includes reactions with arbitrary steps, e.g. $kA\to(k+r)A$. Employing WKB approximation, controlled by a large system size, we evaluate both the exponent and the pre-exponential factor for the rate. The results are illustrated on a number of examples. %U http://arxiv.org/abs/0811.0090v1