%0 Journal Article
%T The Changing Geometry of a Fitness Landscape Along an Adaptive Walk
%A Devin Greene
%A Kristina Crona
%J Quantitative Biology
%D 2013
%I arXiv
%R 10.1371/journal.pcbi.1003520
%X It has recently been noted that the relative prevalence of the various kinds of epistasis varies along an adaptive walk. This has been explained as a result of mean regression in NK model fitness landscapes. Here we show that this phenomenon occurs quite generally in fitness landscapes. We propose a simple and general explanation for this phenomemon, confirming the role of mean regression. We provide support for this explanation with simulations, and discuss the empirical relevance of our findings.
%U http://arxiv.org/abs/1307.1918v3