%0 Journal Article %T Critical Scale-invariance in Healthy Human Heart Rate %A Ken Kiyono %A Zbigniew R. Struzik %A Naoko Aoyagi %A Seiichiro Sakata %A Junichiro Hayano %A Yoshiharu Yamamoto %J Quantitative Biology %D 2004 %I arXiv %R 10.1103/PhysRevLett.93.178103 %X We demonstrate the robust scale-invariance in the probability density function (PDF) of detrended healthy human heart rate increments, which is preserved not only in a quiescent condition, but also in a dynamic state where the mean level of heart rate is dramatically changing. This scale-independent and fractal structure is markedly different from the scale-dependent PDF evolution observed in a turbulent-like, cascade heart rate model. These results strongly support the view that healthy human heart rate is controlled to converge continually to a critical state. %U http://arxiv.org/abs/q-bio/0409039v1