%0 Journal Article %T Small Open Chemical Systems Theory and Its Implications to Darwinian Evolutionary Dynamics, Complex Self-Organization and Beyond %A Hong Qian %J Quantitative Biology %D 2012 %I arXiv %R 10.1088/0253-6102/62/4/12 %X The study of biological cells in terms of mesoscopic, nonequilibrium, nonlinear, stochastic dynamics of open chemical systems provides a paradigm for other complex, self-organizing systems with ultra-fast stochastic fluctuations, short-time deterministic nonlinear dynamics, and long-time evolutionary behavior with exponentially distributed rare events, discrete jumps among punctuated equilibria, and catastrophe. %U http://arxiv.org/abs/1203.3874v2