%0 Journal Article
%T Amino acid classes and the protein folding problem
%A Marek Cieplak
%A Neal S. Holter
%A Amos Maritan
%A Jayanth R. Banavar
%J Quantitative Biology
%D 2000
%I arXiv
%R 10.1063/1.1333025
%X We present and implement a distance-based clustering of amino acids within the framework of a statistically derived interaction matrix and show that the resulting groups faithfully reproduce, for well-designed sequences, thermodynamic stability in and kinetic accessibility to the native state. A simple interpretation of the groups is obtained by eigenanalysis of the interaction matrix.
%U http://arxiv.org/abs/cond-mat/0010244v1