%0 Journal Article %T Morphogenesis of membrane invaginations in spherical confinement %A Osman Kahraman %A Norbert Stoop %A Martin Michael Mueller %J Physics %D 2012 %I arXiv %R 10.1209/0295-5075/97/68008 %X We study the morphology of a fluid membrane in spherical confinement. When the area of the membrane is slightly larger than the area of the outer container, a single axisymmetric invagination is observed. For higher area, self-contact occurs: the invagination breaks symmetry and deforms into an ellipsoid-like shape connected to its outer part via a small slit. For even higher areas, a second invagination forms inside the original invagination. The folding patterns observed could constitute basic building blocks in the morphogenesis of biological tissues and organelles. %U http://arxiv.org/abs/1201.2518v2