%0 Journal Article %T Multimodal Imaging of Human Brain Activity: Rational, Biophysical Aspects and Modes of Integration %A Katarzyna Blinowska %A Gernot M¨šller-Putz %A Vera Kaiser %A Laura Astolfi %A Katrien Vanderperren %A Sabine Van Huffel %A Louis Lemieux %J Computational Intelligence and Neuroscience %D 2009 %I Hindawi Publishing Corporation %R 10.1155/2009/813607 %X Until relatively recently the vast majority of imaging and electrophysiological studies of human brain activity have relied on single-modality measurements usually correlated with readily observable or experimentally modified behavioural or brain state patterns. Multi-modal imaging is the concept of bringing together observations or measurements from different instruments. We discuss the aims of multi-modal imaging and the ways in which it can be accomplished using representative applications. Given the importance of haemodynamic and electrophysiological signals in current multi-modal imaging applications, we also review some of the basic physiology relevant to understanding their relationship. %U http://www.hindawi.com/journals/cin/2009/813607/