%0 Journal Article %T The spectrum of isotropic diffuse gamma-ray emission between 100 MeV and 820 GeV %A The Fermi LAT collaboration %A M. Ackermann %A M. Ajello %A A. Albert %A W. B. Atwood %A L. Baldini %A J. Ballet %A G. Barbiellini %A D. Bastieri %A K. Bechtol %A R. Bellazzini %A E. Bissaldi %A R. D. Blandford %A E. D. Bloom %A E. Bottacini %A T. J. Brandt %A J. Bregeon %A P. Bruel %A R. Buehler %A S. Buson %A G. A. Caliandro %A R. A. Cameron %A M. Caragiulo %A P. A. Caraveo %A E. Cavazzuti %A C. Cecchi %A E. Charles %A A. Chekhtman %A J. Chiang %A G. Chiaro %A S. Ciprini %A R. Claus %A J. Cohen-Tanugi %A J. Conrad %A A. Cuoco %A S. Cutini %A F. D'Ammando %A A. de Angelis %A F. de Palma %A C. D. Dermer %A S. W. Digel %A E. do Couto e Silva %A P. S. Drell %A C. Favuzzi %A E. C. Ferrara %A W. B. Focke %A A. Franckowiak %A Y. Fukazawa %A S. Funk %A P. Fusco %A F. Gargano %A D. Gasparrini %A S. Germani %A N. Giglietto %A P. Giommi %A F. Giordano %A M. Giroletti %A G. Godfrey %A G. A. Gomez-Vargas %A I. A. Grenier %A S. Guiriec %A M. Gustafsson %A D. Hadasch %A K. Hayashi %A E. Hays %A J. W. Hewitt %A P. Ippoliti %A T. Jogler %A G. J¨®hannesson %A A. S. Johnson %A W. N. Johnson %A T. Kamae %A J. Kataoka %A J. Kn£¿dlseder %A M. Kuss %A S. Larsson %A L. Latronico %A J. Li %A L. Li %A F. Longo %A F. Loparco %A B. Lott %A M. N. Lovellette %A P. Lubrano %A G. M. Madejski %A A. Manfreda %A F. Massaro %A M. Mayer %A M. N. Mazziotta %A J. E. McEnery %A P. F. Michelson %A W. Mitthumsiri %A T. Mizuno %A A. A. Moiseev %A M. E. Monzani %A A. Morselli %A I. V. Moskalenko %A S. Murgia %A R. Nemmen %A E. Nuss %A T. Ohsugi %A N. Omodei %A E. Orlando %A J. F. Ormes %A D. Paneque %A J. H. Panetta %A J. S. Perkins %A M. Pesce-Rollins %A F. Piron %A G. Pivato %A T. A. Porter %A S. Rain¨° %A R. Rando %A M. Razzano %A S. Razzaque %A A. Reimer %A O. Reimer %A T. Reposeur %A S. Ritz %A R. W. Romani %A M. S¨¢nchez-Conde %A M. Schaal %A A. Schulz %A C. Sgr¨° %J Physics %D 2014 %I arXiv %R 10.1088/0004-637X/799/1/86 %X The {\gamma}-ray sky can be decomposed into individually detected sources, diffuse emission attributed to the interactions of Galactic cosmic rays with gas and radiation fields, and a residual all-sky emission component commonly called the isotropic diffuse {\gamma}-ray background (IGRB). The IGRB comprises all extragalactic emissions too faint or too diffuse to be resolved in a given survey, as well as any residual Galactic foregrounds that are approximately isotropic. The first IGRB measurement with the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope (Fermi) used 10 months of sky-survey data and considered an energy range between 200 MeV and 100 GeV. Improvements in event selection and characterization of cosmic-ray backgrounds, better understanding of the diffuse Galactic emission, and a longer data accumulation of 50 months, allow for a refinement and extension of the IGRB measurement with the LAT, now covering the energy range from 100 MeV to 820 GeV. The IGRB spectrum shows a significant high-energy cutoff feature, and can be well described over nearly four decades in energy by a power law with exponential cutoff having a spectral index of $2.32\pm0.02$ and a break energy of $(279\pm52)$ GeV using our baseline diffuse Galactic emission model. The total intensity attributed to the IGRB is $(7.2\pm0.6) \times 10^{-6}$ cm$^{-2}$ s$^{-1}$ sr$^{-1}$ above 100 MeV, with an additional $+15$%/$-30$% systematic uncertainty due to the Galactic diffuse foregrounds. %U http://arxiv.org/abs/1410.3696v1