%0 Journal Article %T Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination %A Maarten Criel %A Filip Geurs %A Siegfried Ponette %A Katrien Bulte %A Johan Ponette %J Case Reports in Hepatology %D 2012 %I Hindawi Publishing Corporation %R 10.1155/2012/138381 %X Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of cisplatin and gemcitabine combination chemotherapy in these patients. Tolerability was good and liver function tests gradually improved. %U http://www.hindawi.com/crim/hepatology/2012/138381/