%0 Journal Article
%T Association of Inflammatory and Oxidative Stress Markers with Metabolic Syndrome in Asian Indians in India
%A Veena S. Rao
%A Radhika K. Nagaraj
%A Sridhara Hebbagodi
%A Natesha B. Kadarinarasimhiah
%A Vijay V. Kakkar
%J Cardiology Research and Practice
%D 2011
%I Hindawi Publishing Corporation
%R 10.4061/2011/295976
%X Metabolic syndrome (MetS) is a primary risk factor for cardiovascular disease and is associated with a proinflammatory state. Here, we assessed the contribution of inflammatory and oxidative stress markers towards prediction of MetS. A total of 2316 individuals were recruited in Phase I of the Indian Atherosclerosis Research Study (IARS). Modified ATPIII guidelines were used for classification of subjects with MetS. Among the inflammatory and oxidative stress markers studied, levels of hsCRP (<.0001), Neopterin (=.036), and oxLDL (<.0001) were significantly higher among subjects with MetS. Among the markers we tested, oxLDL stood out as a robust predictor of MetS in the IARS population (OR 4.956 95% CI 2.504–9.810; <.0001) followed by hsCRP (OR 1.324 95% CI 1.070–1.638; =.010). In conclusion, oxLDL is a candidate predictor for MetS in the Asian Indian population.
%U http://www.hindawi.com/journals/crp/2011/295976/