%0 Journal Article
%T Lectins with Anti-HIV Activity: A Review
%A Ouafae Akkouh
%A Tzi Bun Ng
%A Senjam Sunil Singh
%A Cuiming Yin
%A Xiuli Dan
%A Yau Sang Chan
%A Wenliang Pan
%A Randy Chi Fai Cheung
%J Molecules
%P 648-668
%D 2015
%I MDPI AG
%R 10.3390/molecules20010648
%X Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins , and the nonpeptidic lectin mimics pradimicins and benanomicins, exhibit anti-HIV activity. The anti-HIV plant lectins include Artocarpus heterophyllus (jacalin) lectin, concanavalin A, Galanthus nivalis (snowdrop) agglutinin-related lectins, Musa acuminata (banana) lectin, Myrianthus holstii lectin, Narcissus pseudonarcissus lectin, and Urtica diocia agglutinin. The anti-HIV algal lectins comprise Boodlea coacta lectin, Griffithsin, Oscillatoria agardhii agglutinin. The anti-HIV cyanobacterial lectins are cyanovirin- N, scytovirin, Microcystis viridis lectin , and microvirin. Actinohivin is an anti-HIV actinomycete lectin. The anti-HIV worm lectins include Chaetopterus variopedatus polychaete marine worm lectin, Serpula vermicularis sea worm lectin, and C-type lectin Mermaid from nematode ( Laxus oneistus) . The anti-HIV nonpeptidic lectin mimics comprise pradimicins and benanomicins. Their anti-HIV mechanisms are discussed.
%K lectins
%K anti-HIV
%K worm
%K cyanobacteria
%K actinomycete
%U http://www.mdpi.com/1420-3049/20/1/648