%0 Journal Article
%T 2,3,4,9-Tetrahydro-9-(3-hydroxy-1,4-dioxo-1H-dihydro-naphthalen-2-yl)-8-methoxy-3,3-dimethyl-1H-xanthen-1-one
%A Eito Yoshioka
%A Shigeru Kohtani
%A Hideto Miyabe
%J Molbank
%D 2015
%I MDPI AG
%R 10.3390/M841
%X The title compound 2,3,4,9-tetrahydro-9-(3-hydroxy-1,4-dioxo-1 H-dihydro-naphthalen-2-yl)-8-methoxy-3,3-dimethyl-1 H-xanthen-1-one ( 5) was obtained by the nucleophilic addition of 2-hydroxy-1,4-naphthoquinone ( 4) to 2 H-chromene derivative 3, which was prepared by the domino three-component coupling reaction of aryne precursor 1 with DMF and the active methylene compound dimedone ( 2). The one-pot synthesis of the title compound 5 from aryne precursor 1 was also achieved.
%K multi-component reaction
%K domino reaction
%K arynes
%K heterocycles
%K synthesis
%U http://www.mdpi.com/1422-8599/2015/1/M841