%0 Journal Article %T PhyloSift: phylogenetic analysis of genomes and metagenomes %A Aaron E. Darling %A Guillaume Jospin %A Eric Lowe %A Frederick A. Matsen IV %A Holly M. Bik %A Jonathan A. Eisen %J PeerJ %D 2015 %I %R 10.7717/peerj.243 %X Like all organisms on the planet, environmental microbes are subject to the forces of molecular evolution. Metagenomic sequencing provides a means to access the DNA sequence of uncultured microbes. By combining DNA sequencing of microbial communities with evolutionary modeling and phylogenetic analysis we might obtain new insights into microbiology and also provide a basis for practical tools such as forensic pathogen detection. %K Metagenomics %K Phylogenetics %K Forensics %K Bayes factor %K Microbial diversity %K Community structure %K Microbial ecology %K Edge PCA %K Phylogenetic diversity %K Microbial evolution %U https://peerj.com/articles/243/