%0 Journal Article %T Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury %A Frans J. Walther %A Jos¨¦ M. Hern¨˘ndez-Juviel %A Larry M. Gordon %A Alan J. Waring %J PeerJ %D 2015 %I %R 10.7717/peerj.393 %X Background. Chemical spills are on the rise and inhalation of toxic chemicals may induce chemical acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Although the pathophysiology of ALI/ARDS is well understood, the absence of specific antidotes has limited the effectiveness of therapeutic interventions. %K Synthetic surfactant %K Hydrochloric acid %K Oxygenation %K Ventilated rabbits %K Surfactant protein B %K Lung lavage %K Acute lung injury %K Surfactant protein C %K Lung compliance %K Captive bubble surfactometry %U https://peerj.com/articles/393/