%0 Journal Article
%T Glycopolymer Code Based on Well-Defined Glycopolymers or Glyconanomaterials and Their Biomolecular Recognition
%A Gokhan Yilmaz
%A C. Remzi Becer
%J Frontiers in Bioengineering and Biotechnology
%D 2014
%I Frontiers Media
%R 10.3389/fbioe.2014.00039
%X Advances in the glycopolymer technology have allowed the preparation of more complex and well-defined glycopolymers/particles with several architectures from linear to globular structures (such as micelles, dendrimers, and nanogels). In the last decade, functionalized self-assembled/decided nano-objects and scaffolds containing glycopolymers were designed to develop many biological and biomedical applications in diseases treatments such as pathogen detection, inhibitors of toxins, and lectin-based biosensors. These studies will facilitate the understanding and investigation of the sugar code on the carbohydrate¨Clectin interactions, which are significantly influenced by the glycopolymer architecture, valency, size, and density of binding elements. In this context, these advanced and selected glycopolymers/particles showing specific interactions with various lectins are highlighted.
%K glycopolymers
%K glycoparticles
%K well-defined polymers
%K biological functionalities
%K recognition events and drug delivery system
%U http://www.frontiersin.org/Journal/10.3389/fbioe.2014.00039/abstract