%0 Journal Article
%T Evaluation of a New Modification of Pancreaticogastrostomy after Pancreaticoduodenectomy: Anastomosis of the Pancreatic Duct to the Gastric Mucosa with Invagination of the Pancreatic Remnant End into the Posterior Gastric Wall for Patients with Cancer Head of Pancreas and Periampullary Carcinoma in terms of Postoperative Pancreatic Fistula Formation
%A Mohamed Mazloum Osman
%A Walid Abd El Maksoud
%J International Journal of Surgical Oncology
%D 2014
%I Hindawi Publishing Corporation
%R 10.1155/2014/490386
%X Background/Objectives. Postoperative pancreatic fistula (POPF) remains the main problem after pancreaticoduodenectomy and determines to a large extent the final outcome. We describe a new modification of pancreaticogastrostomy which combines duct to mucosa anastomosis with suturing the pancreatic capsule to posterior gastric wall and then invaginating the pancreatic remnant into the posterior gastric wall. This study was designed to assess the results of this new modification of pancreaticogastrostomy. Methods. The newly modified pancreaticogastrostomy was applied to 37 consecutive patients after pancreaticoduodenectomy for periampullary cancer (64.86%) or cancer head of the pancreas (35.14%). Eighteen patients (48.65%) had a soft pancreatic remnant, 13 patients (35.14%) had firm pancreatic remnant, and 6 patients (16.22%) had intermediate texture of pancreatic remnant. Rate of mortality, early postoperative complications, and hospital stay were also reported. Results. Operative mortality was zero and morbidity was 29.73%. Only three patients (8.11%) developed pancreatic leaks; they were treated conservatively. Eight patients (16.1%) had delayed gastric emptying, one patient (2.70%) had minor hemorrhage, one patient (2.70%) had biliary leak, and four patients (10.81%) had superficial wound infection. Conclusions. The new modified pancreatogastrostomy seems safe and reliable with low rate of POPF. However, further prospective controlled trials are essential to support these results. 1. Introduction Pancreaticoduodenectomy (PD) is a procedure commonly performed for malignant and some benign diseases of the pancreatic head [1]. In the past, mortality rate after pancreaticoduodenectomy was very high. Nowadays, with the advancement of imaging studies, surgical techniques, and perioperative management, the mortality rate of pancreaticoduodenectomy has decreased to 0¨C9%. However, in most of the recent series morbidity rate remains high (30¨C50%), even at high volume centers [2, 3]. Postoperative pancreatic fistula (POPF) is the most common complication of pancreaticoduodenectomy. It is a critical trigger of life-threatening complications such as intra-abdominal abscess and hemorrhage [4]. It leads to prolongation of hospital stay, severe morbidity, or even surgical mortality. The incidence of POPF is reported to be 0¨C17% based on a variety of definitions [5, 6]. In the literature, there is no consensus toward the superiority of either pancreaticojejunostomy (PJ) or pancreaticogastrostomy (PG) as the best method for reconstruction after pancreaticoduodenectomy.
%U http://www.hindawi.com/journals/ijso/2014/490386/