%0 Journal Article
%T 尿酸和血清胱抑素C对高血压肾损害早期诊断的预测价值<br>Prediction of Renal Damage Complicated by Hypertension With Uric Acid and Serum Cystatin C as Early Marker
%A 彭家清
%J Advances in Clinical Medicine
%P 25-28
%@ 2161-8720
%D 2013
%I Hans Publishing
%R 10.12677/ACM.2013.34007
%X <div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">目的</span><span style=\"line-height:1.5;\">:</span><span style=\"line-height:1.5;\"> </span><span style=\"line-height:1.5;\">探讨血尿酸和血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">对高血压肾损害的早期诊断价值。</span><span style=\"line-height:1.5;\">方法</span><span style=\"line-height:1.5;\">:</span><span style=\"line-height:1.5;\"> </span><span style=\"line-height:1.5;\">前瞻性纳入我院收治的原发性高血压患者</span><span style=\"line-height:1.5;\">151</span><span style=\"line-height:1.5;\">例。根据是否并发肾损害，将患者分为单纯高血压组</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">I</span><span style=\"line-height:1.5;\">组</span><span style=\"line-height:1.5;\">)</span><span style=\"line-height:1.5;\">和高血压肾损害组</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">Ⅱ组</span><span style=\"line-height:1.5;\">)</span><span style=\"line-height:1.5;\">，采用全自动生化分析仪同时测定血清尿酸、肌酐和尿素氮，免疫透射比浊法测定血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">含量，并与健康体检者</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">对照组</span><span style=\"line-height:1.5;\">)</span><span style=\"line-height:1.5;\">相关指标作对比研究，并进行相关分析，评价血尿酸和血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">对高血压肾损害早期诊断的价值。</span><span style=\"line-height:1.5;\">结果</span><span style=\"line-height:1.5;\">：</span><span style=\"line-height:1.5;\">I</span><span style=\"line-height:1.5;\">组、Ⅱ组血尿酸和血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">的阳性率明显高于对照组</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">P </span><span style=\"line-height:1.5;\">&lt; 0.01)</span><span style=\"line-height:1.5;\">。同组患者血尿酸和血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">的阳性率明显高于其血尿素和血肌酐阳性率</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">P </span><span style=\"line-height:1.5;\">&lt; 0.01)</span><span style=\"line-height:1.5;\">。此外，高血压患者血尿酸和血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">的升高早于血尿素和血肌酐。</span><span style=\"line-height:1.5;\">结论</span><span style=\"line-height:1.5;\">: </span><span style=\"line-height:1.5;\">血尿酸和血清胱抑素</span><span style=\"line-height:1.5;\">C</span><span style=\"line-height:1.5;\">是反映高血压早期肾功能损害的敏感指标，其敏感度高于血尿素和血肌酐，在诊断高血压早期肾损害方面有重要的临床价值。&lt;br/</span><span style=\"line-height:1.5;\">&gt;</span><span style=\"line-height:1.5;\">Abstract:
%K 尿酸；胱抑素C；高血压；早期肾损害<br>Uric Acid
%K Cystatin C
%K Hypertension
%K Early Impairment of Renal Function
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=12888