%0 Journal Article
%T Synthesis and Guest-Binding Behavior of Water-Soluble Cyclophanes Bearing PEG  Residues
%A Osamu Hayashida
%A Yuki Nakamura
%A Takuya Sato
%J Advances in Chemical Engineering and Science
%P 409-416
%@ 2160-0406
%D 2014
%I Scientific Research Publishing
%R 10.4236/aces.2014.44045
%X A water-soluble
cyclophane (1) having poly(ethylene glycol) (PEG) moieties has been prepared
from a tetraazide-functionalized cyclophane derivative and four poly(ethylene
glycol) methyl ether acetylenes by Cu(I)-catalyzed 1,3 dipolar cycloadditions
(click chemistry). An analogous derivative having a pyrene moiety (2) was also
prepared in a similar manner. The guest-binding behavior of 1 and 2 toward
anionic guests such as 6-<i>p</i>-toluidinonaphthalene-2-sulfonate
was investigated by fluorescence spectroscopy. The binding constants (<i>K</i>) of the host-guest complexes were
evaluated.
%K Host-Guest Chemistry
%K Water-Soluble Cyclophane
%K Poly(Ethylene Glycol)
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49974