%0 Journal Article
%T Reaction of Nitrilimines with 2-Aminopicoline, 3-Amino-1,2,4-Triazole, 5-Aminotetrazole and 2-Aminopyrimidine
%A Rami Y. Morjan
%A Basam S. Qeshta
%A Hussein T. Al-Shayyah
%A John M. Gardiner
%A Basam A. Abu-Thaher
%A Adel M. Awadallah
%J International Journal of Organic Chemistry
%P 201-207
%@ 2161-4695
%D 2014
%I Scientific Research Publishing
%R 10.4236/ijoc.2014.43023
%X The reaction of picoline derivatives 3-6 with hydrazonoylhalide 1a produced imidazo[1,2-a]pyridines 7-10, while the reaction of the same picoline derivatives with hydrazonoylhalide 1b afforded imidazo[1,2-a]pyridine-2-ones 11-13. The reaction of 1b, c with 3-amino-1,2,4-triazole 14 produced the acyclic adducts 18 and 19, respectively. Reaction of 1b, 1c with 5-aminotetrazole 20 produced the acyclic products 23 and 24, respectively. Finally, the reaction of 1b with 4, 6-dimethyl-2-aminopyrimidine 27 afforded compound 29 rather than its isomeric structure 28. The structure of the products was confirmed by the different spectroscopic analytical methods including IR, MS, <sup>1</sup>HNMR and <sup>13</sup>CNMR.<em></em><em></em>
%K Nitrilimines
%K Picolines
%K Imidazo[1
%K 2-a]Pyridine
%K Triazoles
%K Tetrazoles
%K Pyrimidines
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49755